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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX3
All Species:
1.52
Human Site:
S251
Identified Species:
3.03
UniProt:
Q13761
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13761
NP_001026850.1
415
44356
S251
D
P
R
Q
F
D
R
S
F
P
T
L
P
T
L
Chimpanzee
Pan troglodytes
XP_001168112
361
38974
F198
P
R
Q
F
D
R
S
F
P
T
L
P
T
L
T
Rhesus Macaque
Macaca mulatta
XP_001113682
501
52667
C337
A
S
G
S
V
P
S
C
P
T
V
V
D
S
L
Dog
Lupus familis
XP_544492
414
44288
Q251
N
P
F
S
D
P
R
Q
F
D
R
S
F
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q64131
409
43610
F246
P
F
S
D
P
R
Q
F
D
R
S
F
P
T
L
Rat
Rattus norvegicus
Q63046
450
48538
Y260
S
Y
D
Q
S
Y
Q
Y
L
G
S
I
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232978
334
36473
P171
E
L
S
P
F
S
D
P
R
Q
F
D
R
S
F
Frog
Xenopus laevis
Q6PF39
462
50351
G298
E
L
S
S
R
L
S
G
A
S
D
L
T
A
F
Zebra Danio
Brachydanio rerio
NP_571679
424
45996
L255
L
R
W
T
S
T
D
L
F
Q
Q
R
T
S
F
Tiger Blowfish
Takifugu rubipres
NP_001092121
407
44638
L243
T
C
K
V
E
E
D
L
R
P
W
P
G
T
T
Fruit Fly
Dros. melanogaster
Q9W349
826
84703
N503
L
V
Q
Q
L
S
S
N
Y
S
S
P
N
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9ATN1
302
31144
A139
L
N
P
S
L
T
I
A
F
A
A
L
R
H
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
63
48.6
N.A.
91.5
59.5
N.A.
N.A.
68.9
56.9
68.1
67.9
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
68.2
56.1
N.A.
94.6
70.4
N.A.
N.A.
74.2
69
75.2
77.3
33.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
20
N.A.
20
6.6
N.A.
N.A.
6.6
6.6
6.6
13.3
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
20
26.6
N.A.
33.3
33.3
N.A.
N.A.
20
13.3
13.3
26.6
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
30.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
9
9
9
0
0
9
9
% A
% Cys:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
9
17
9
25
0
9
9
9
9
9
0
0
% D
% Glu:
17
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
9
9
17
0
0
17
34
0
9
9
9
0
34
% F
% Gly:
0
0
9
0
0
0
0
9
0
9
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
17
0
0
17
9
0
17
9
0
9
25
0
9
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
9
0
0
0
0
9
0
0
% N
% Pro:
17
17
9
9
9
17
0
9
17
17
0
25
17
9
0
% P
% Gln:
0
0
17
25
0
0
17
9
0
17
9
0
0
0
0
% Q
% Arg:
0
17
9
0
9
17
17
0
17
9
9
9
17
0
0
% R
% Ser:
9
9
25
34
17
17
34
9
0
17
25
9
0
42
9
% S
% Thr:
9
0
0
9
0
17
0
0
0
17
9
0
34
25
25
% T
% Val:
0
9
0
9
9
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
9
0
0
0
9
0
9
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _